Rapid imaging of internal microstructures in tissue specimens

The Histolog® Scanner

The Histolog Scanner is a digital microscopy system for high-resolution imaging of fresh tissue surfaces without slicing or damaging the sample. Simply dip the intact specimen in a contrast agent for a few seconds, place it on the device, and scan.

Based on massively parallel confocal microscopy, a breakthrough proprietary and patented technology developed by SamanTree Medical, it enables ultra-fast, on-site tissue visualization while preserving the specimen for further analysis.

It is available for sale in the EU, US and many other countries around the world.

Histolog Scanner for intraoperative margin assessment

Rapid, high-resolution imaging at the site of care.

15
seconds

Specimen prep time

~1
minute

Scan time per surface

17 cm2
surface

Imaging window: 4.8 x 3.6 cm

2 µm
per pixel

Resolution

Two medical professionals in scrubs and gloves examining a tissue sample on a computer screen in a laboratory.

Rapid tissue imaging

Specimen surface imaging in minutes without resource-intensive processing

High-resolution

Confocal microscopy delivers high resolution images to provide additional information and assist decision-making by physicians.

Easy to use

User-friendly platform with digital capabilities. Maintain integrity of specimen for final pathology.

Imaging and physician evaluation in 4 easy steps with the Histolog Scanner

Collect fresh tissue for imaging.

1.

Immerse specimen in Histolog Dip for 10 second, then rinse for 2-5 seconds in saline.

2.

Place the specimen on Histolog Dish, and scan its surface (imaging takes ~1 min)

3.

Review images on-site or remotely with physician collaboration tool.

4.

Device intended for qualified healthcare professionals only.

Examples of High-Resolution Images

Allows physicians to rapidly visualize and evaluate tissue microstructures

Histolog physician collaboration tools

Digital collaboration tools allow physicians to review images remotely, whether together in real time or at their own pace. These platforms let users view high-resolution images, make detailed annotations, and highlight areas of interest, making it easier to share insights and consult with colleagues.

The Histolog Dip and Dish

The Histolog Dip is a patented fluorescent stain specifically formulated for use with the Histolog Scanner. It is prepared at physiological pH, osmolarity, and ion concentrations to preserve cellular integrity. It shows no interference with downstream pathology tests such as H&E and immunohistochemistry.

The Histolog Dish is single-use, patented device made with high-grade optical film for high-resolution imaging. It offers high transparency, low haze, and precise thickness, is clean-room manufactured to be dust-free, protects the imaging window, and features a self-centering design for easy placement on the Histolog Scanner.

Two medical professionals in scrubs and gloves working with a histology slide in a laboratory

Medical team of three doctors or surgeons in green scrubs, wearing surgical masks and caps, examining an image on a computer screen in a hospital or surgical room.

Two scientists in white lab coats working in a laboratory, one seated at a microscope and the other operating a histology scanner with a purple stained tissue sample on the screen.

Refer to the Histolog IFU for full instructions for use. All data on file at SamanTree Medical.

A&P-00464 V1 - WW